Matrix-assisted Laser Desorption/Ionization Mass Spectra Study of Complexed Alkaloid from Colchicum Species
Joanna Kurek *
Faculty of Chemistry, A. Mickiewicz University, Umultowska 89b, 61-614 Poznań, Poland
Grażyna Bartkowiak
Faculty of Chemistry, A. Mickiewicz University, Umultowska 89b, 61-614 Poznań, Poland
Grzegorz Schroeder
Faculty of Chemistry, A. Mickiewicz University, Umultowska 89b, 61-614 Poznań, Poland
*Author to whom correspondence should be addressed.
Abstract
Complexes are biologically useful compounds and they have many biological activities. Colchicine can form stable complexes with alkali metals. Till now colchicine complexes have not been characterised by modern mass spectra methods such as MALDI MS (Matrix-assisted laser desorption/ionization mass spectral). The aim of this study was to check fragmentation pathways of colchicine complexes with alkali metals: Li+, Na+, K+ by MALDI MS mass spectra. The colchicine complexes with Li+, Na+, K+ cations of perchlorates and iodides have been synthesised and studied in details by MALDI MS mass spectra.
Keywords: Colchicine complexes, MALDI MS mass spectra, MALDI TOF MS