Journal of Materials Science Research and Reviews

Solvent-free Mechanochemical Synthesis, Characterization and Antibacterial Potency of CaO@SiO2 Nanocomposite

Danbature Wilson Lamayi

Department of Chemistry, Faculty of Science, Gombe State University, Gombe, Nigeria.

Mela Yoro

Department of Chemical Sciences, Faculty of Science, Federal University, Kashere, Gombe, Nigeria.

Zaccheus Shehu *

Department of Chemistry, Faculty of Science, Gombe State University, Gombe, Nigeria.

Yakong David Madugu

Department of Chemistry, Faculty of Science, Gombe State University, Gombe, Nigeria.

Sani Ibrahim Aliyu

Microbiology Laboratory, Gombe State University, Gombe, Nigeria.

*Author to whom correspondence should be addressed.

---

Abstract

Objectives: This aim of this study was to synthesized CaO@SiO₂ nanocomposite using solvent-free mechanochemical method and applied against gram-positive bacteria (Bacillus subtilis, Klebsiella pneunoniae) and gram-negative bacteria (Pseudomonas aeruginasa, Escherichia coli, and Salmonella typhi).

Methods: The structure of CaO@SiO₂ nanocomposite was confirmed by FTIR and UV-Visible spectroscopy. Agar well diffusion method was used for the antibacterial studies. The antibacterial activity of CaO@SiO₂ nanocomposite was found to be dose dependent. The zone of inhibition decreases in the following order; S. typhi, P. aeruginosa, K. pneumoniae, B. subtilis and E. coli.

Conclusions: CaO@SiO₂ nanocomposite showed excellent antibacterial activity and can be used as promising antibacterial agent.

Keywords: CaO@SiO2 Nanocomposite, antibacterial, mechanochemical synthesis, solvent-free, environmentally friendly

---

---